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KMID : 0860920050070010040
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2005 Volume.7 No. 1 p.40 ~ p.44
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The Change of Nerve Conduction Study Parameters in Rats by Complex Regional Pain Syndrome Model
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Ko Young-Jin
Park Geun-Young
Lee Jong-In
Choi Hang-Joon
Hong Hyeon-Taek
Kim Jae-Min
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Abstract
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Objectives: To verify the type of complex regional pain syndrome (CRPS) at Bennett and Xie’s model1
through the nerve conduction study.
Method: Twenty male Sprague-Dawley rats were divided into control and experimental group. The control
group had sham operations. The model of Bennett and Xie had a chronic constriction injury for the
experimental group. For each group, the thickness and the temperature of the right hind paw and the
weight of subjects were measured before, two weeks and four weeks after the operation. Also, the motor
nerve conduction study was done in right sciatic nerve.
Result: After two and four weeks of the operation, the thickness and the temperature of the right hind
paw in the experimental group were significantly higher than those of the control group. In the motor
nerve conduction study, the amplitude of compound muscle action potential in the experimental group
was significantly decreased.
Conclusion: This results suggest that Bennett and Xie’s model is CRPS type II.
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KEYWORD
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CRPS (Complex regional pain syndrome), Chronic construction injury, Nerve conduction study, Rat model, Sciatic nerve
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